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Several subseries of registers recording the admission and discharge of individuals to the county home in the period 1914-1957. The earliest register in this series was opened in 1914, and can also be viewed as the last register for the Tullamore Workhouse, which closed in 1921.

Several subseries of registers of admissions and discharges to the county hospital for the period 1932-1948, and also includes medical reports and prescriptions from the period 1919-1950.

Registers, slightly overlapping between the years 1932 and 1943, of deaths recorded as having taken place in the workhouse (1913-1921), the county home (1922-1947), and the hospitals (1932-1943) under the care of firstly Tullamore Poor Law Union and immediately succeeded by Offaly Board of Health and Public Assistance.

Series of annual reports with many gaps, compiled by the County Medical Officer of Health. The first extant report from 1929 focuses mainly on statistics gathered from inspections of the the national schools in the county. Topics covered include dental health, ophthalmic clinics, tonsil and adenoid operations, enlarged cervical glands, 'mental defectives', tuberculosis, malnutrition, vaccination, skin diseases, defective speech, rheumatism, deformities, open-air education, co-operation of parents, sanitation and environment of schools,

Later annual reports refer to the health and sanitary conditions in the county as a whole while also incorporating the school medical service report. This broadened report contains general statistics of the county, vital statistics, water and sewage reports, housing, lists of midwives, notification of births, notifications of infectious disease, diptheria immunisation, sanitary administration, food and drug samples, venereal disease scheme, school meals free milk scheme, welfare of the blind, district nursing associations, meat and milk inspections, bovine T. B. and the annual report of the clinical tuberculosis officer.